{"id":1470,"date":"2025-02-27T09:15:37","date_gmt":"2025-02-27T01:15:37","guid":{"rendered":"https:\/\/xiaoenjiyao.com\/?p=1470"},"modified":"2025-02-27T09:15:38","modified_gmt":"2025-02-27T01:15:38","slug":"fda%e5%b7%b2%e8%8e%b7%e6%89%b9%e5%85%8d%e7%96%ab%e6%a3%80%e6%9f%a5%e7%82%b9pd-1-pd-l1%e6%8a%91%e5%88%b6%e5%89%82%e6%9b%b4%e6%96%b0-%e6%88%aa%e6%ad%a22025-01-21","status":"publish","type":"post","link":"https:\/\/xiaoenjiyao.com\/?p=1470","title":{"rendered":"FDA\u5df2\u83b7\u6279\u514d\u75ab\u68c0\u67e5\u70b9PD-1\/PD-L1\u6291\u5236\u5242\u66f4\u65b0 | \u622a\u6b622025-01-21"},"content":{"rendered":"\n<p>2023\u5e74\uff0c\u672c\u53f7\u66fe\u6c47\u603b\u4e86FDA\u5df2\u83b7\u6279\u7684\u514d\u75ab\u68c0\u67e5\u70b9PD-1\/PD-L1\u6291\u5236\u5242\u7684\u83b7\u6279\u60c5\u51b5\u53ca\u9002\u5e94\u75c7\uff0c\u5305\u62ec\uff1a<\/p>\n\n\n\n<p><strong>PD-1\u6291\u5236\u5242\uff1a<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u53ef\u745e\u8fbe\u00ae \u5e15\u535a\u5229\u73e0\u5355\u6297\uff08KEYTRUDA\u00ae pembrolizumab\uff09<\/li>\n\n\n\n<li>\u6b27\u72c4\u6c83\u00ae \u7eb3\u6b66\u5229\u5c24\u5355\u6297\uff08OPDIVO\u00ae nivolumab\uff09<\/li>\n\n\n\n<li>LIBTAYO\u00ae cemiplimab<\/li>\n\n\n\n<li>JEMPERLI\u00ae dostarlimab<\/li>\n\n\n\n<li>ZYNYZ\u00ae retifanlimab<\/li>\n<\/ul>\n\n\n\n<p><strong>PD-L1\u6291\u5236\u5242\uff1a<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u6cf0\u5723\u5947\u00ae \u963f\u66ff\u5229\u73e0\u5355\u6297\uff08TECENTRIQ\u00ae atezolizumab\uff09<\/li>\n\n\n\n<li>\u82f1\u98de\u51e1\u00ae \u5ea6\u4f10\u5229\u5c24\u5355\u6297\uff08IMFINZI\u00ae durvalumab\uff09<\/li>\n\n\n\n<li>BAVENCIO\u00ae avelumab<\/li>\n<\/ul>\n\n\n\n<p>\u65f6\u9694\u4e24\u5e74\uff0c\u8fd9\u4e9b\u836f\u7269\u7684\u9002\u5e94\u75c7\u5747\u6709\u6240\u6269\u5c55\uff0c\u5e76\u4e14\u53c8\u6709\u4e24\u6b3e\u65b0\u836f\u83b7\u5f97FDA\u6279\u51c6\u4e0a\u5e02\uff0c\u5206\u522b\u662f\uff1a<\/p>\n\n\n\n<p><strong>\u767e\u6cfd\u5b89\u00ae \u66ff\u96f7\u5229\u73e0\u5355\u6297\uff08Tevimbra\u00ae Tislelizumab\uff09<\/strong><\/p>\n\n\n\n<p>\u7531\u767e\u6d4e\u795e\u5dde\u81ea\u4e3b\u5f00\u53d1\u7684\u4e00\u6b3ePD-1\u6291\u5236\u5242\u5355\u514b\u9686\u6297\u4f53\u3002\u8be5\u836f\u7269\u6700\u65e9\u4e8e2019\u5e74\u5728\u56fd\u5185\u4e0a\u5e02\uff0c\u7ecf\u8fc7\u4e94\u5e74\u7684\u51fa\u6d77\u52aa\u529b\uff0c\u4e8e2024\u5e743\u6708\u83b7\u5f97\u7f8e\u56fdFDA\u6279\u51c6\u4e0a\u5e02\uff0c\u6210\u4e3a\u9996\u4e2a\u83b7FDA\u6279\u51c6\u7684\u56fd\u4ea7PD-1\u836f\u7269\u3002<\/p>\n\n\n\n<p><strong>UNLOXCYT\u00ae Cosibelimab<\/strong><\/p>\n\n\n\n<p>\u7531Checkpoint 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\u5e15\u535a\u5229\u73e0\uff0c\u7eb3\u6b66\u5229\u5c24\uff0c\u963f\u66ff\u5229\u73e0\uff0c\u5ea6\u4f10\u5229\u5c24\u5355\u6297\u7b49<\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">2\u3001\u9002\u5e94\u75c7<\/h2>\n\n\n\n<p>\u514d\u75ab\u6cbb\u7597\u7684\u6838\u5fc3\u601d\u60f3\u662f\u91cd\u65b0\u6fc0\u6d3b\u673a\u4f53\u81ea\u8eab\u7684\u514d\u75ab\u7cfb\u7edf\u6765\u62b5\u6297\u80bf\u7624\u7ec6\u80de\u3002<\/p>\n\n\n\n<p>\u56e0\u6b64\u514d\u75ab\u6cbb\u7597\u7406\u8bba\u4e0a\u53ef\u4ee5\u4e0d\u9650\u764c\u79cd\uff0c\u8bc6\u522b\u5e76\u653b\u51fb\u591a\u79cd\u80bf\u7624\u7ec6\u80de\uff0c\u8fbe\u5230\u6291\u5236\u80bf\u7624\u751f\u957f\u548c\u6269\u6563\u7684\u76ee\u7684\u3002<\/p>\n\n\n\n<p>\u73b0\u5c06\u622a\u6b622025\u5e741\u670821\u65e5\uff0cFDA\u5df2\u7ecf\u83b7\u6279\u7684PD-1\u548cPD-L1\u836f\u7269\u7684\u9002\u5e94\u75c7\u603b\u7ed3\u5982\u4e0b\uff1a<\/p>\n\n\n\n<p><strong>PD-1\u6291\u5236\u5242FDA\u9002\u5e94\u75c7\uff1a<\/strong><\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"1550\" height=\"1368\" src=\"https:\/\/xiaoenjiyao.com\/wp-content\/uploads\/2025\/02\/image-2.png\" alt=\"\" class=\"wp-image-1474\" srcset=\"https:\/\/xiaoenjiyao.com\/wp-content\/uploads\/2025\/02\/image-2.png 1550w, https:\/\/xiaoenjiyao.com\/wp-content\/uploads\/2025\/02\/image-2-300x265.png 300w, https:\/\/xiaoenjiyao.com\/wp-content\/uploads\/2025\/02\/image-2-1024x904.png 1024w, https:\/\/xiaoenjiyao.com\/wp-content\/uploads\/2025\/02\/image-2-768x678.png 768w, https:\/\/xiaoenjiyao.com\/wp-content\/uploads\/2025\/02\/image-2-1536x1356.png 1536w, https:\/\/xiaoenjiyao.com\/wp-content\/uploads\/2025\/02\/image-2-1218x1075.png 1218w, https:\/\/xiaoenjiyao.com\/wp-content\/uploads\/2025\/02\/image-2-880x777.png 880w\" sizes=\"auto, (max-width: 1550px) 100vw, 1550px\" \/><\/figure>\n\n\n\n<p><strong>PD-L1\u6291\u5236\u5242FDA\u9002\u5e94\u75c7\uff1a<\/strong><\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img 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