{"id":1478,"date":"2025-02-27T09:27:12","date_gmt":"2025-02-27T01:27:12","guid":{"rendered":"https:\/\/xiaoenjiyao.com\/?p=1478"},"modified":"2025-02-27T09:27:12","modified_gmt":"2025-02-27T01:27:12","slug":"%e8%ae%b0%e4%bd%8ffda%e4%b8%8a%e5%b8%82%e7%94%9f%e7%89%a9%e8%8d%af-%e6%b2%bb%e7%96%97a%e5%9e%8bb%e5%9e%8b%e8%a1%80%e5%8f%8b%e7%97%85-concizumab-%e5%ba%b7%e8%b5%9b%e7%8f%a0%e5%8d%95%e6%8a%97","status":"publish","type":"post","link":"https:\/\/xiaoenjiyao.com\/?p=1478","title":{"rendered":"\u8bb0\u4f4fFDA\u4e0a\u5e02\u751f\u7269\u836f | \u6cbb\u7597A\u578bB\u578b\u8840\u53cb\u75c5 | Concizumab \u5eb7\u8d5b\u73e0\u5355\u6297 | \u6297TFPI"},"content":{"rendered":"\n<p>Concizumab\u662f\u8bfa\u548c\u8bfa\u5fb7\uff08Novo Nordisk\uff09\u5f00\u53d1\u7684\u4e00\u6b3e\u9488\u5bf9\u7ec4\u7ec7\u56e0\u5b50\u9014\u5f84\u6291\u5236\u5242\uff08TFPI\uff09\u7684\u5355\u514b\u9686\u6297\u4f53\u3002<\/p>\n\n\n\n<p>\u836f\u7269\u4e8e2024\u5e7412\u6708\u83b7\u5f97FDA\u6279\u51c6\uff08Alhemo\u00ae concizumab\uff09\uff0c\u9002\u7528\u4e8e\u6cbb\u7597\u8840\u53cb\u75c5A\u548c\u8840\u53cb\u75c5B\u60a3\u8005\u3002<\/p>\n\n\n\n<p>\u76ee\u524d\u8be5\u836f\u7269\u5c1a\u672a\u5728\u56fd\u5185\u4e0a\u5e02\uff0c\u4e2d\u6587\u540d\u79f0\u6682\u8bd1\u4e3a\u5eb7\u8d5b\u73e0\u5355\u6297\uff08\u97f3\u8bd1\u65e0\u51fa\u5904\uff09\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">1\u3001\u4f5c\u7528\u673a\u5236<\/h2>\n\n\n\n<p>\u7531\u4e8eConcizumab\u4e0e\u4e0a\u4e2a\u6708FDA\u6279\u51c6\u4e0a\u5e02\u7684\u8f89\u745e\u516c\u53f8\u7684HYMPAVZI\u00ae marstacimab\u9a6c\u5854\u897f\u5355\u6297\u4f5c\u7528\u673a\u5236\u4e00\u81f4\uff0c\u5927\u5bb6\u51fa\u95e8\u5de6\u8f6c\uff0c\u8bf7\u53c2\u8003\u6211\u524d\u7bc7\u7684\u5185\u5bb9\u3002<\/p>\n\n\n\n<p><a href=\"https:\/\/mp.weixin.qq.com\/s?__biz=Mzg2NTgyNzcyMQ==&amp;mid=2247491761&amp;idx=1&amp;sn=18fbb6bc7b90f8846ba01946c2649c5c&amp;scene=21#wechat_redirect\">\u8bb0\u4f4fFDA\u4e0a\u5e02\u751f\u7269\u836f | \u6cbb\u7597A\u578bB\u578b\u8840\u53cb\u75c5 | Marstacimab\u9a6c\u5854\u897f\u5355\u6297 | \u6297TFPI<\/a><\/p>\n\n\n\n<p>\u73b0\u5c06\u4e24\u6b3e\u9488\u5bf9TFPI \u7684\u751f\u7269\u5236\u5242\u7684\u4e0d\u540c\u70b9\u603b\u7ed3\u5982\u4e0b\uff1a<\/p>\n\n\n\n<figure class=\"wp-block-table\"><table class=\"has-fixed-layout\"><tbody><tr><td><\/td><td><strong>Alhemo<\/strong><strong>\u00ae&nbsp;<\/strong><strong>Concizumab<\/strong><strong><br>&nbsp; &nbsp;<\/strong><strong>\u5eb7\u8d5b\u73e0\u5355\u6297<\/strong><\/td><td><strong>Hympavzi\u00ae Marstacimab<br>&nbsp; &nbsp;<\/strong><strong>\u9a6c\u5854\u897f\u5355\u6297<\/strong><\/td><\/tr><tr><td><strong>\u7597\u6548<\/strong><strong>(<\/strong><strong>ABR<\/strong><strong>\u51cf\u5c11)<\/strong><\/td><td>\u5e74\u5316\u51fa\u8840\u7387\u964d\u4f4e&nbsp;86%<\/td><td>\u5e74\u5316\u51fa\u8840\u7387\u964d\u4f4e&nbsp;91.6%<\/td><\/tr><tr><td><strong>\u9002\u7528\u4eba\u7fa4<\/strong><\/td><td>\u6709VIII\u548cIX\u6291\u5236\u7269\u7684\u8840\u53cb\u75c5A\u6216B\u60a3\u8005(\u226512\u5c81)<\/td><td>\u65e0VIII\u548cIX\u6291\u5236\u7269\u7684\u8840\u53cb\u75c5A\u6216B\u60a3\u8005(\u226512\u5c81)<\/td><\/tr><tr><td><strong>\u7ed9\u836f\u9891\u7387<\/strong><\/td><td>\u6bcf\u65e5\u4e00\u6b21\u76ae\u4e0b\u6ce8\u5c04<\/td><td>\u6bcf\u5468\u4e00\u6b21\u76ae\u4e0b\u6ce8\u5c04<\/td><\/tr><tr><td><strong>\u5b89\u5168\u6027<\/strong><\/td><td>\u8010\u53d7\u6027\u826f\u597d\uff0c\u8bd5\u9a8c\u4e2d\u66fe\u6709\u8840\u6813\u4e8b\u4ef6\uff0c\u8c03\u6574\u540e\u65e0\u65b0\u62a5<\/td><td>\u8010\u53d7\u6027\u826f\u597d\uff0c\u65e0\u8840\u6813\u4e8b\u4ef6\u62a5\u544a<\/td><\/tr><tr><td><strong>\u5e38\u89c1\u526f\u4f5c\u7528<\/strong><\/td><td>\u6ce8\u5c04\u90e8\u4f4d\u53cd\u5e94\u3001\u8368\u9ebb\u75b9\u3001\u8f7b\u5ea6\u8fc7\u654f\u53cd\u5e94<\/td><td>\u6ce8\u5c04\u90e8\u4f4d\u53cd\u5e94\u3001\u8f7b\u5ea6\u8fc7\u654f\u3001\u77ed\u6682\u8840\u538b\u5347\u9ad8<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\">2\u3001\u9002\u5e94\u75c7<\/h2>\n\n\n\n<p>Concizumab\u662f\u4e00\u79cd\u7ec4\u7ec7\u56e0\u5b50\u9014\u5f84\u6291\u5236\u5242\uff08TFPI\uff09\u62ee\u6297\u5242\uff0c\u9002\u7528\u4e8e12\u5c81\u53ca\u4ee5\u4e0a\u7684\u6210\u4eba\u548c\u513f\u7ae5\u60a3\u8005\uff0c\u7528\u4e8e\u5e38\u89c4\u9884\u9632\u4ee5\u51cf\u5c11\u6216\u964d\u4f4e\u51fa\u8840\u4e8b\u4ef6\u7684\u9891\u7387\u3002<\/p>\n\n\n\n<p>\u9002\u5e94\u4eba\u7fa4\u5305\u62ec\uff1a<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u8840\u53cb\u75c5A\uff08\u5148\u5929\u6027FVIII\u7f3a\u4e4f\u75c7\uff09\u4f34\u968fFVIII\u6291\u5236\u5242\u7684\u60a3\u8005<\/li>\n\n\n\n<li>\u8840\u53cb\u75c5B\uff08\u5148\u5929\u6027FIX\u7f3a\u4e4f\u75c7\uff09\u4f34\u968fFIX\u6291\u5236\u5242\u7684\u60a3\u8005<\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">3\u3001\u56fe\u50cf\u8bb0\u5fc6<\/h2>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"598\" src=\"https:\/\/xiaoenjiyao.com\/wp-content\/uploads\/2025\/02\/image-4-1024x598.png\" alt=\"\" class=\"wp-image-1479\" srcset=\"https:\/\/xiaoenjiyao.com\/wp-content\/uploads\/2025\/02\/image-4-1024x598.png 1024w, https:\/\/xiaoenjiyao.com\/wp-content\/uploads\/2025\/02\/image-4-300x175.png 300w, https:\/\/xiaoenjiyao.com\/wp-content\/uploads\/2025\/02\/image-4-768x448.png 768w, https:\/\/xiaoenjiyao.com\/wp-content\/uploads\/2025\/02\/image-4-1536x897.png 1536w, https:\/\/xiaoenjiyao.com\/wp-content\/uploads\/2025\/02\/image-4-2048x1196.png 2048w, https:\/\/xiaoenjiyao.com\/wp-content\/uploads\/2025\/02\/image-4-1218x711.png 1218w, https:\/\/xiaoenjiyao.com\/wp-content\/uploads\/2025\/02\/image-4-880x514.png 880w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><figcaption class=\"wp-element-caption\"><em>\u4e00\u5339\u9a6c\u8e29\u5728\u5854\u4e0a\uff0c\u4e0b\u9762\u662f\u897f\u74dc\u3002\u897f\u74dc\u4e0b\u9762\u4e00\u4e2a\u5751\uff0c\u91cc\u9762\u4e00\u5934\u6b7b\u732a\u3002\u5854\u8fd8\u653e\u4e86\u4e2a\u81ed\u5c41\u3002<\/em><\/figcaption><\/figure>\n\n\n\n<p>\u9a6c-\u5854-\u897f\u74dc\uff0c\u4ee3\u8868\u7b2c\u4e00\u4e2a\u836f\u7269\uff0c\u9a6c\u5854\u897f\u5355\u6297\u3002<\/p>\n\n\n\n<p>\u5751\u91cc\u7684\u6b7b\u732a\uff0c\u4ee3\u8868\u7b2c\u4e8c\u4e2a\u836f\u7269\uff0c\u5eb7\u585e\u73e0\u5355\u6297\u3002<\/p>\n\n\n\n<p>\u5854\u5728\u653e\u5c41\uff0c\u4ee3\u8868\u836f\u7269\u9776\u70b9TFPI\u3002<\/p>\n\n\n\n<p>\u800c\u5730\u4e0a\u4e00\u6ee9\u8840\uff0c\u4ee3\u8868\u836f\u7269\u9002\u5e94\u75c7\uff0cA\u578b\u548cB\u578b\u8840\u53cb\u75c5\u3002<\/p>\n\n\n\n<p>\u4f60\u8bb0\u4f4f\u4e86\u4e48<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Concizumab\u662f\u8bfa\u548c\u8bfa\u5fb7\uff08N&#8230;<\/p>\n","protected":false},"author":1,"featured_media":1481,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[3],"tags":[],"class_list":["post-1478","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-3","wpcat-3-id"],"_links":{"self":[{"href":"https:\/\/xiaoenjiyao.com\/index.php?rest_route=\/wp\/v2\/posts\/1478","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/xiaoenjiyao.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/xiaoenjiyao.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/xiaoenjiyao.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/xiaoenjiyao.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=1478"}],"version-history":[{"count":1,"href":"https:\/\/xiaoenjiyao.com\/index.php?rest_route=\/wp\/v2\/posts\/1478\/revisions"}],"predecessor-version":[{"id":1482,"href":"https:\/\/xiaoenjiyao.com\/index.php?rest_route=\/wp\/v2\/posts\/1478\/revisions\/1482"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/xiaoenjiyao.com\/index.php?rest_route=\/wp\/v2\/media\/1481"}],"wp:attachment":[{"href":"https:\/\/xiaoenjiyao.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=1478"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/xiaoenjiyao.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=1478"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/xiaoenjiyao.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=1478"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}