{"id":341,"date":"2022-09-06T10:26:49","date_gmt":"2022-09-06T02:26:49","guid":{"rendered":"https:\/\/xiaoenjiyao.com\/?p=341"},"modified":"2022-09-06T10:26:49","modified_gmt":"2022-09-06T02:26:49","slug":"%e5%9b%be%e5%83%8f%e8%ae%b0%e5%bf%86-tnf%e6%8b%ae%e6%8a%97%e5%89%82-%e4%be%9d%e9%82%a3%e8%a5%bf%e6%99%ae-%e6%81%a9%e5%88%a9-etanercept-%e7%b1%bb%e9%a3%8e%e6%b9%bf%e5%85%b3%e8%8a%82%e7%82%8e","status":"publish","type":"post","link":"https:\/\/xiaoenjiyao.com\/?p=341","title":{"rendered":"\u56fe\u50cf\u8bb0\u5fc6 | TNF\u62ee\u6297\u5242 | \u4f9d\u90a3\u897f\u666e | \u6069\u5229 | Etanercept | \u7c7b\u98ce\u6e7f\u5173\u8282\u708e\u3001\u5f3a\u76f4\u6027\u810a\u67f1\u708e\u751f\u7269\u836f"},"content":{"rendered":"\n<p>\u7528\u56fe\u50cf\u8bb0\u5fc6\uff0c\u4e00\u4e2a\u836f\u4e00\u5f20\u56fe\uff0c\u8bb0\u4f4f\u751f\u7269\u836f\u7684\u540d\u79f0\uff0c\u9776\u70b9\uff0c\u9002\u5e94\u75c7\u7b49\u4fe1\u606f\u3002<\/p>\n\n\n\n<p>\u8f89\u745e\uff08Pfizer\uff09\u516c\u53f8\u7684\u80bf\u7624\u574f\u6b7b\u56e0\u5b50(Tumor necrosis factor\uff0cTNF)\u62ee\u6297\u5242\u7c7b\u751f\u7269\u5236\u5242\uff0c\u6069\u5229<sup>\u00ae<\/sup>\u4f9d\u90a3\u897f\u666e\uff0cENBREL<sup>\u00ae<\/sup>&nbsp;(etanercept) \uff0c1998\u5e74\u5373\u83b7FDA\u6279\u51c6\u4e0a\u5e02\u3002<\/p>\n\n\n\n<p>\u8be5\u836f\u7269\u56fd\u5185\u5df2\u7ecf\u83b7\u6279\u4e0a\u5e02\u3002\u76ee\u524d\u83b7\u6279\u9002\u5e94\u75c7\u4e3a\u7c7b\u98ce\u6e7f\u5173\u8282\u708e\u3001\u5f3a\u76f4\u6027\u810a\u67f1\u708e\u3002<\/p>\n\n\n\n<h2 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\/><figcaption><em><em>mmunotherapy . 2018 Mar 1;10(6):433-445.<\/em><\/em><\/figcaption><\/figure>\n<\/div>\n\n\n<p>\u4f9d\u90a3\u897f\u666e\u662f\u7531\u7ec6\u80de\u8868\u9762TNF\u53d7\u4f53\u878d\u5408\u81f3\u4ebaIgG1\u7684Fc\u6bb5\u5f62\u6210\u7684\u4e8c\u805a\u4f53\u878d\u5408\u86cb\u767d\u3002<\/p>\n\n\n\n<p>TNF\u53d7\u4f53\u6709\u4e24\u79cd\u7c7b\u578b\uff1a<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>\u4e00\u79cd\u662f\u7ec6\u80de\u8868\u9762\u7684\u53d7\u4f53\uff0c\u80fd\u4e0eTNF\u7ed3\u5408\uff0c\u6fc0\u6d3b\u4fe1\u53f7\u901a\u8def\uff1b<\/li><li>\u53e6\u4e00\u79cd\u5219\u662f\u6e38\u79bb\u53d7\u4f53\uff0c\u5206\u5e03\u5728\u7ec4\u7ec7\u6db2\u4e2d\uff0c\u4e0eTNF\u7ed3\u5408\u540e\u4e0d\u6fc0\u6d3b\u4fe1\u53f7\u901a\u8def\uff0c\u8d77\u5230\u964d\u4f4e\u8fc7\u591a\u6e38\u79bbTNF\u542b\u91cf\u7684\u4f5c\u7528\u3002<\/li><\/ul>\n\n\n\n<p><strong>\u4f9d\u90a3\u897f\u666e\u7684\u4f5c\u7528<\/strong><\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large 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