{"id":360,"date":"2022-09-11T22:27:29","date_gmt":"2022-09-11T14:27:29","guid":{"rendered":"https:\/\/xiaoenjiyao.com\/?p=360"},"modified":"2022-09-27T19:25:31","modified_gmt":"2022-09-27T11:25:31","slug":"5%e6%ac%betnf%e6%8b%ae%e6%8a%97%e5%89%82-%e4%be%9d%e9%82%a3%e8%a5%bf%e6%99%ae-%e8%8b%b1%e5%a4%ab%e5%88%a9%e8%a5%bf%e5%8d%95%e6%8a%97-%e9%98%bf%e8%be%be%e6%9c%a8%e5%8d%95%e6%8a%97-%e5%9f%b9","status":"publish","type":"post","link":"https:\/\/xiaoenjiyao.com\/?p=360","title":{"rendered":"5\u6b3eTNF\u62ee\u6297\u5242 |  \u4f9d\u90a3\u897f\u666e | \u82f1\u592b\u5229\u897f\u5355\u6297 | \u963f\u8fbe\u6728\u5355\u6297 | \u57f9\u585e\u5229\u73e0\u5355\u6297 |  \u6208\u5229\u6728\u5355\u6297 \u53ca\u603b\u7ed3"},"content":{"rendered":"\n<p>\u7528\u56fe\u50cf\u8bb0\u5fc6\uff0c\u4e00\u4e2a\u836f\u4e00\u5f20\u56fe\uff0c\u8bb0\u4f4f\u751f\u7269\u836f\u7684\u540d\u79f0\uff0c\u9776\u70b9\uff0c\u9002\u5e94\u75c7\u7b49\u4fe1\u606f\u3002<\/p>\n\n\n\n<p>TNF\u62ee\u6297\u5242\u7c7b\u751f\u7269\u5236\u5242\uff0c\u9664\u4e86\u524d\u6587\u8bb2\u7684\u4f9d\u90a3\u897f\u666e\u548c\u82f1\u592b\u5229\u897f\u5355\u6297\u5916\uff0c\u76ee\u524dFDA\u6279\u51c6\u4e0a\u5e02\u7684\u8fd8\u67093\u6b3e\uff0c\u5206\u522b\u4e3a\uff1a\u4fee\u7f8e\u4e50\u00ae\u963f\u8fbe\u6728\u5355\u6297 Adalimumab\u3001\u5e0c\u654f\u4f73\u00ae\u57f9\u585e\u5229\u73e0\u5355\u6297 Certolizumab\u3001\u6b23\u666e\u5c3c\u00ae\u6208\u5229\u6728\u5355\u6297Golimumab\u3002<\/p>\n\n\n\n<p>\u76ee\u524d5\u6b3e\u836f\u7269\u56fd\u5185\u5747\u5df2\u4e0a\u5e02\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">1\u30015\u6b3eTNF\u62ee\u6297\u5242\u7ed3\u6784\u7279\u70b9<\/h2>\n\n\n\n<p>5\u6b3eTNF\u62ee\u6297\u5242\u7684\u5206\u5b50\u7ed3\u6784\uff0c\u4f5c\u7528\u673a\u5236\uff0c\u7b49\u5404\u6709\u7279\u70b9\u3002<\/p>\n\n\n\n<p>\u4f9d\u90a3\u897f\u666e\u548c\u82f1\u592b\u5229\u897f\u5355\u6297\u4e3a\u6700\u65e9\u4e0a\u5e02\u7684TNF\u62ee\u6297\u5242\u7c7b\u751f\u7269\u5236\u5242\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>\u4f9d\u90a3\u897f\u666e<\/strong>\u4e3a\u878d\u5408\u86cb\u767d\uff0c\u65e2\u53ef\u6291\u5236TNF\u03b1\uff0c\u53c8\u53ef\u6291\u5236TNF\u03b2\u3002<\/li><li><strong>\u82f1\u592b\u5229\u897f\u5355\u6297<\/strong>\u4e3a\u4eba\u9f20\u5d4c\u5408\u5355\u514b\u9686\u6297\u4f53\uff0c\u4e0e\u53e6\u59164\u6b3e\u751f\u7269\u5236\u5242\u4e00\u6837\u7279\u5f02\u6027\u6291\u5236TNF\u03b1\u3002<\/li><\/ul>\n\n\n\n<p><strong>\u963f\u8fbe\u6728\u5355\u6297<\/strong>\u4e3a\u5168\u4eba\u6e90\u5355\u6297\uff0c\u514d\u75ab\u539f\u6027\u6bd4\u82f1\u592b\u5229\u897f\u5355\u6297\u66f4\u4f4e\u3002<\/p>\n\n\n\n<p><strong>\u57f9\u585e\u5229\u73e0\u5355\u6297<\/strong>\u4e3aFab\u6297\u4f53\u7247\u6bb5\uff0c\u7ed3\u6784\u4e2d\u7528\u805a\u4e59\u4e8c\u9187PEG\u4ee3\u66ff\u6297\u4f53\u7684Fc\u6bb5\uff0c\u907f\u514dFc\u6bb5\u5f15\u8d77\u7684ADCC\u548cCDC\u4f5c\u7528\uff0c\u5b89\u5168\u6027\u66f4\u597d\u3002\u53e6\u5916\u4e5f\u907f\u514d\u4e86Fc\u6bb5\u4e0e\u65b0\u751f\u513f\u53d7\u4f53FcRn\u7ed3\u5408\uff0c\u836f\u7269\u4e0d\u4f1a\u7ecf\u8fc7\u80ce\u76d8\u5c4f\u969c\uff0c\u598a\u5a20\u671f\u5987\u5973\u53ef\u4ee5\u5b89\u5168\u4f7f\u7528\u3002<\/p>\n\n\n\n<p><strong>\u6208\u5229\u6728\u5355\u6297<\/strong>\u4eba\u6e90\u5316\u7a0b\u5ea6\u6700\u9ad8\uff0c\u8fbe99.1%\uff0c\u6297\u836f\u6297\u4f53ADA\u53d1\u751f\u7387\u4ec53.8%\uff0c\u4f18\u4e8e\u963f\u8fbe\u6728\u5355\u6297\u3002\u53e6\u5916\u5bf9TNF\u03b1\u4eb2\u548c\u529b\u4e3a\u963f\u8fbe\u6728\u5355\u6297\u76843-6\u500d\u3002\u7ed9\u836f\u9891\u7387\u66f4\u4f4e\uff0c\u6bcf\u6708\u4ec5\u9700\u4e00\u6b21\u3002<\/p>\n\n\n\n<p><strong>5\u6b3eTNF\u62ee\u6297\u5242\u6c47\u603b\u5982\u4e0b\uff1a<\/strong><\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large is-resized\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/xiaoenjiyao.com\/wp-content\/uploads\/2022\/09\/image-29-1024x521.png\" alt=\"\" class=\"wp-image-446\" width=\"792\" height=\"403\" srcset=\"https:\/\/xiaoenjiyao.com\/wp-content\/uploads\/2022\/09\/image-29-1024x521.png 1024w, https:\/\/xiaoenjiyao.com\/wp-content\/uploads\/2022\/09\/image-29-300x153.png 300w, https:\/\/xiaoenjiyao.com\/wp-content\/uploads\/2022\/09\/image-29-768x391.png 768w, https:\/\/xiaoenjiyao.com\/wp-content\/uploads\/2022\/09\/image-29-1536x782.png 1536w, https:\/\/xiaoenjiyao.com\/wp-content\/uploads\/2022\/09\/image-29-1218x620.png 1218w, https:\/\/xiaoenjiyao.com\/wp-content\/uploads\/2022\/09\/image-29-880x448.png 880w, https:\/\/xiaoenjiyao.com\/wp-content\/uploads\/2022\/09\/image-29.png 1788w\" sizes=\"auto, (max-width: 792px) 100vw, 792px\" \/><figcaption><em>5\u6b3eTNF\u62ee\u6297\u5242<\/em><\/figcaption><\/figure>\n<\/div>\n\n\n<h2 class=\"wp-block-heading\">2\u3001\u9002\u5e94\u75c7<\/h2>\n\n\n\n<p>TNF\u4e3aTh1\u578b\u901a\u8def\u5e38\u89c1\u7ec6\u80de\u56e0\u5b50\uff0c\u5bf9\u5173\u8282\u708e\uff0c\u810a\u67f1\u708e\uff0c\u94f6\u5c51\u75c5\uff0c\u708e\u75c7\u6027\u80a0\u75c5\u7b49\u8d77\u5173\u952e\u4f5c\u7528\u3002<\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large is-resized\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/xiaoenjiyao.com\/wp-content\/uploads\/2022\/09\/image-13-1024x511.png\" alt=\"\" class=\"wp-image-363\" width=\"789\" height=\"394\" srcset=\"https:\/\/xiaoenjiyao.com\/wp-content\/uploads\/2022\/09\/image-13-1024x511.png 1024w, https:\/\/xiaoenjiyao.com\/wp-content\/uploads\/2022\/09\/image-13-300x150.png 300w, https:\/\/xiaoenjiyao.com\/wp-content\/uploads\/2022\/09\/image-13-768x384.png 768w, https:\/\/xiaoenjiyao.com\/wp-content\/uploads\/2022\/09\/image-13-1536x767.png 1536w, https:\/\/xiaoenjiyao.com\/wp-content\/uploads\/2022\/09\/image-13-1218x608.png 1218w, https:\/\/xiaoenjiyao.com\/wp-content\/uploads\/2022\/09\/image-13-880x439.png 880w, https:\/\/xiaoenjiyao.com\/wp-content\/uploads\/2022\/09\/image-13.png 1558w\" sizes=\"auto, (max-width: 789px) 100vw, 789px\" \/><figcaption><em>5\u6b3eTNF\u62ee\u6297\u5242<\/em>\u9002\u5e94\u75c7<\/figcaption><\/figure>\n<\/div>\n\n\n<h2 class=\"wp-block-heading\">3\u3001\u56fe\u50cf\u8bb0\u5fc6<\/h2>\n\n\n\n<p>\u7531\u4e8e\u4fe1\u606f\u8f83\u591a\uff0c\u7528\u4e24\u5f20\u56fe\u8bb0\u5fc6\u3002<\/p>\n\n\n\n<p><strong>\u9996\u5148\u7528\u7b2c\u4e00\u5f20\u56fe\u8bb0\u4f4f\u67095\u6b3eTNF\u62ee\u6297\u5242<\/strong><\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large is-resized\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/xiaoenjiyao.com\/wp-content\/uploads\/2022\/09\/image-17-1024x624.png\" alt=\"\" class=\"wp-image-371\" width=\"632\" height=\"384\" srcset=\"https:\/\/xiaoenjiyao.com\/wp-content\/uploads\/2022\/09\/image-17-1024x624.png 1024w, https:\/\/xiaoenjiyao.com\/wp-content\/uploads\/2022\/09\/image-17-300x183.png 300w, https:\/\/xiaoenjiyao.com\/wp-content\/uploads\/2022\/09\/image-17-768x468.png 768w, https:\/\/xiaoenjiyao.com\/wp-content\/uploads\/2022\/09\/image-17-1218x742.png 1218w, https:\/\/xiaoenjiyao.com\/wp-content\/uploads\/2022\/09\/image-17-880x536.png 880w, https:\/\/xiaoenjiyao.com\/wp-content\/uploads\/2022\/09\/image-17.png 1352w\" sizes=\"auto, (max-width: 632px) 100vw, 632px\" \/><figcaption><em>\u82f1\u56fd\u7684\u963f\u80cc\u54e5\u4e0e\u53cd\u5bf9\u515a\u4f9d\u59d3\u5973\u515a\u9b41\uff0c\u5173\u4e8e\u80bf\u7624\u7ec6\u80de\u7684\u4e8b\u9879\u5c55\u5f00\u8bae\u4f1a\u8fa9\u8bba\uff0c\u6700\u7ec8\u9996\u76f8\u4e0d\u654c\uff0c\u88ab\u8feb\u4e0b\u53f0\uff0c\u4fdd\u5b88\u515a\u4e5f\u6362\u4e0a\u4e86\u5973\u6027\u9996\u76f8\u3002<\/em><\/figcaption><\/figure>\n<\/div>\n\n\n<p>\u80bf\u7624\u7ec6\u80de\u4ee3\u8868\u80bf\u7624\u574f\u6b7b\u56e0\u5b50TNF\u62ee\u6297\u5242\u3002<\/p>\n\n\n\n<p>\u4f9d\u59d3\u515a\u9b41\u3001\u82f1\u56fd\u963f\u80cc\u54e5\uff0c\u90fd\u53d6\u7b2c\u4e00\u4e2a\u5b57\uff0c\u5206\u522b\u4ee3\u8868\u4f9d\u90a3\u897f\u666e\u3001\u82f1\u592b\u5229\u897f\u5355\u6297\u3001\u963f\u8fbe\u6728\u5355\u6297\u3001\u57f9\u585e\u5229\u73e0\u5355\u6297\u3001\u6208\u5229\u6728\u5355\u6297\u3002<\/p>\n\n\n\n<p><strong>\u7b2c\u4e8c\u5f20\u56fe\u8bb0\u4f4f\u6bcf\u4e00\u4e2aTNF\u62ee\u6297\u5242\u7684\u540d\u5b57<\/strong><\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large is-resized\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/xiaoenjiyao.com\/wp-content\/uploads\/2022\/09\/image-18-1024x744.png\" alt=\"\" class=\"wp-image-372\" width=\"581\" height=\"422\" srcset=\"https:\/\/xiaoenjiyao.com\/wp-content\/uploads\/2022\/09\/image-18-1024x744.png 1024w, https:\/\/xiaoenjiyao.com\/wp-content\/uploads\/2022\/09\/image-18-300x218.png 300w, https:\/\/xiaoenjiyao.com\/wp-content\/uploads\/2022\/09\/image-18-768x558.png 768w, https:\/\/xiaoenjiyao.com\/wp-content\/uploads\/2022\/09\/image-18-880x639.png 880w, https:\/\/xiaoenjiyao.com\/wp-content\/uploads\/2022\/09\/image-18.png 1060w\" sizes=\"auto, (max-width: 581px) 100vw, 581px\" \/><figcaption><em>\u4f9d\u59d3\u5973\u5b50\u4f53\u6e2939.9\uff0c\u5e38\u5e74\u62ff\u7740\u676f\u5b50\u559d\u836f\uff0c\u5e76\u88ab\u9694\u79bb\u5728\u8981\u585e\u91cc\u966a\u4f34\u80bf\u7624\u7ec6\u80de\u3002\u7531\u4e8e\u5979\u5f88\u6709\u94b1\uff0c\u5c31\u7528\u82f1\u9551\u4ed8\u5229\u606f\uff0c\u96c7\u4f63\u94c1\u81c2\u963f\u56fe\u6728\u524d\u6765\u8425\u6551\uff0c\u963f\u56fe\u6728\u795e\u52c7\uff0c\u51b2\u7834\u4e86\u9694\u79bb\u8981\u585e\u7684\u6728\u5934\u95e8\uff0c\u6551\u51fa\u4e86\u7f8e\u4eba\u3002<\/em><\/figcaption><\/figure>\n<\/div>\n\n\n<p>\u80bf\u7624\u7ec6\u80de\u8fd8\u662f\u4ee3\u8868\u80bf\u7624\u574f\u6b7b\u56e0\u5b50TNF\u62ee\u6297\u5242\u3002<\/p>\n\n\n\n<p>\u4f9d\u59d3\u5973\u5b50\u62ff\u7740\u8336\u676f\u5c0f\u53e3sip\u559d\u836f\uff0c\u4ee3\u8868\u4f9d\u90a3\u897f\u666e\u3002<\/p>\n\n\n\n<p>\u82f1\u9551\u4ed8\u5229\u606f\uff0c\u4ee3\u8868\u82f1\u592b\u5229\u897f\u5355\u6297\u3002<\/p>\n\n\n\n<p>\u94c1\u81c2\u963f\u56fe\u6728\uff0c\u4ee3\u8868\u963f\u8fbe\u6728\u5355\u6297\u3002<\/p>\n\n\n\n<p>\u5973\u5b50\u966a\u5728\u8981\u585e\u91cc\uff0c\u4ee3\u8868\u57f9\u585e\u5229\u73e0\u5355\u6297\u3002<\/p>\n\n\n\n<p>\u9694\u79bb\u7528\u7684\u6728\u95e8\uff0c\u4ee3\u8868\u6208\u5229\u6728\u5355\u6297\u3002<\/p>\n\n\n\n<p>\u4f60\u8bb0\u4f4f\u4e86\u4e48\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u7528\u56fe\u50cf\u8bb0\u5fc6\uff0c\u4e00\u4e2a\u836f\u4e00\u5f20\u56fe\uff0c\u8bb0\u4f4f\u751f\u7269&#8230;<\/p>\n","protected":false},"author":1,"featured_media":373,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[3],"tags":[],"class_list":["post-360","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-3","wpcat-3-id"],"_links":{"self":[{"href":"https:\/\/xiaoenjiyao.com\/index.php?rest_route=\/wp\/v2\/posts\/360","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/xiaoenjiyao.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/xiaoenjiyao.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/xiaoenjiyao.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/xiaoenjiyao.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=360"}],"version-history":[{"count":5,"href":"https:\/\/xiaoenjiyao.com\/index.php?rest_route=\/wp\/v2\/posts\/360\/revisions"}],"predecessor-version":[{"id":448,"href":"https:\/\/xiaoenjiyao.com\/index.php?rest_route=\/wp\/v2\/posts\/360\/revisions\/448"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/xiaoenjiyao.com\/index.php?rest_route=\/wp\/v2\/media\/373"}],"wp:attachment":[{"href":"https:\/\/xiaoenjiyao.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=360"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/xiaoenjiyao.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=360"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/xiaoenjiyao.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=360"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}