{"id":472,"date":"2022-10-11T09:35:16","date_gmt":"2022-10-11T01:35:16","guid":{"rendered":"https:\/\/xiaoenjiyao.com\/?p=472"},"modified":"2022-11-07T22:39:15","modified_gmt":"2022-11-07T14:39:15","slug":"%e5%a6%82%e4%bd%95%e8%ae%b0%e4%bd%8f%e6%89%80%e6%9c%89fda%e6%89%b9%e5%87%86%e7%94%9f%e7%89%a9%e8%8d%af%ef%bc%9f-%e8%a1%a5%e4%bd%93c3%e6%8a%91%e5%88%b6%e5%89%82-pegcetacoplan-%e5%9f%b9%e8%a5%bf","status":"publish","type":"post","link":"https:\/\/xiaoenjiyao.com\/?p=472","title":{"rendered":"\u5982\u4f55\u8bb0\u4f4f\u6240\u6709FDA\u6279\u51c6\u751f\u7269\u836f\uff1f| \u8865\u4f53C3\u6291\u5236\u5242 | Pegcetacoplan \u57f9\u897f\u8003\u5e03\u4ed1 | \u6cbb\u7597\u9635\u53d1\u6027\u7761\u7720\u6027\u8840\u7ea2\u86cb\u767d\u5c3f\u75c7"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\">\u7528\u56fe\u50cf\u8bb0\u5fc6\u7684\u65b9\u6cd5\uff0c\u4e00\u4e2a\u836f\u4e00\u5f20\u56fe\uff0c\u8bb0\u4f4f\u6240\u6709FDA\u6279\u51c6\u4e0a\u5e02\u7684\u751f\u7269\u5236\u5242\u7684\u540d\u79f0\uff0c\u9776\u70b9\uff0c\u9002\u5e94\u75c7\u7b49\u4fe1\u606f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Pegcetacoplan\u662f\u7531Apellis\u516c\u53f8\u4e0e\u745e\u5178Sobi\u516c\u53f8\u5171\u540c\u5f00\u53d1\u7684\u4e00\u79cd\u805a\u4e59\u4e8c\u9187\u73af\u80bd\uff0c\u7279\u5f02\u6027\u5730\u4e0e\u8865\u4f53C3\u3001C3b\u7ed3\u5408\uff0c\u8c03\u8282\u8865\u4f53\u8fc7\u5ea6\u6fc0\u6d3b\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u8be5\u836f2021\u5e745\u6708\u83b7\u7f8e\u56fdFDA\u6279\u51c6\u4e0a\u5e02\u3002\u836f\u54c1\u540d\u79f0\u4e3aEMPAVELI\u2122 Pegcetacoplan\u3002\u6279\u51c6\u9002\u5e94\u75c7\u4e3a\u7f55\u89c1\u75c5\uff1a\u6210\u4eba\u9635\u53d1\u6027\u7761\u7720\u6027\u8840\u7ea2\u86cb\u767d\u5c3f\u75c7PNH\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u7531\u4e8e\u8be5\u836f\u76ee\u524d\u56fd\u5185\u672a\u4e0a\u5e02\uff0c\u672a\u89c1\u5b98\u65b9\u4e2d\u6587\u540d\uff0c\u56fd\u5185\u4e00\u4e9b\u6587\u732e\u79f0\u5176\u4e3a\u57f9\u897f\u8003\u5e03\u4ed1\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">1\u3001\u4f5c\u7528\u673a\u5236<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u5173\u4e8e\u8865\u4f53\u7684\u4f5c\u7528\uff0c\u53c2\u89c1\u6211\u4e0a\u4e00\u7ae0\u5185\u5bb9\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><a href=\"https:\/\/xiaoenjiyao.com\/?p=461\">\u8865\u4f53C1s\u6291\u5236\u5242 | Sutimlimab \u82cf\u66ff\u5229\u5355\u6297 | \u6cbb\u7597\u51b7\u51dd\u96c6\u7d20\u75c5\uff08CAD\uff09<\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Pegcetacoplan\u57f9\u897f\u8003\u5e03\u4ed1\u9776\u70b9<\/strong><\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large is-resized\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/xiaoenjiyao.com\/wp-content\/uploads\/2022\/10\/image-10-1024x635.png\" alt=\"\" class=\"wp-image-473\" width=\"702\" height=\"434\" srcset=\"https:\/\/xiaoenjiyao.com\/wp-content\/uploads\/2022\/10\/image-10-1024x635.png 1024w, https:\/\/xiaoenjiyao.com\/wp-content\/uploads\/2022\/10\/image-10-300x186.png 300w, https:\/\/xiaoenjiyao.com\/wp-content\/uploads\/2022\/10\/image-10-768x476.png 768w, https:\/\/xiaoenjiyao.com\/wp-content\/uploads\/2022\/10\/image-10-1218x755.png 1218w, https:\/\/xiaoenjiyao.com\/wp-content\/uploads\/2022\/10\/image-10.png 1382w\" sizes=\"auto, (max-width: 702px) 100vw, 702px\" \/><figcaption class=\"wp-element-caption\"><em>Blood . 2022 Jun 9;139(23):3361-3365.<\/em><\/figcaption><\/figure>\n<\/div>\n\n\n<p class=\"wp-block-paragraph\">\u8865\u4f53\u6fc0\u6d3b\u7684\u4e09\u6761\u9014\u5f84\uff1a1\u3001\u7ecf\u5178\u9014\u5f84 2\u3001MBL\u9014\u5f84 3\u3001\u65c1\u8def\u9014\u5f84<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u65e0\u8bba\u54ea\u6761\u9014\u5f84\uff0c\u6700\u7ec8\u90fd\u901a\u8fc7C3-C3b-C5-C9\u7684\u6fc0\u6d3b\u8def\u5f84\u53d1\u6325\u4f5c\u7528\uff0c\u56e0\u6b64\u4e0e\u4e0a\u4e00\u7ae0Sutimlimab\u82cf\u66ff\u5229\u5355\u6297\u9776\u5411C1\uff0c\u4ec5\u6291\u5236\u7ecf\u5178\u9014\u5f84\u76f8\u6bd4\uff0c\u836f\u7269\u9776\u5411C3\u80fd\u6291\u5236\u5168\u90e8\u8865\u4f53\u901a\u8def\uff0c\u4f5c\u7528\u66f4\u5e7f\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">2\u3001\u9002\u5e94\u75c7<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u9635\u53d1\u6027\u7761\u7720\u6027\u8840\u7ea2\u86cb\u767d\u5c3f\u75c7(paroxysmal nocturnal hemoglobinuria, PNH)\u662f\u4e00\u79cd\u83b7\u5f97\u6027\u9020\u8840\u5e72\u7ec6\u80de\u57fa\u56e0\u7a81\u53d8\u5f15\u8d77\u7684\uff0c\u5371\u53ca\u751f\u547d\u7684\u8840\u6db2\u7cfb\u7edf\u7f55\u89c1\u75be\u75c5\uff0c\u5168\u7403\u60a3\u75c5\u7387\u7ea6\u4e3a16-20\/100\u4e07\u3002<\/p>\n\n\n\n<p 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srcset=\"https:\/\/xiaoenjiyao.com\/wp-content\/uploads\/2022\/10\/image-11-1024x518.png 1024w, https:\/\/xiaoenjiyao.com\/wp-content\/uploads\/2022\/10\/image-11-300x152.png 300w, https:\/\/xiaoenjiyao.com\/wp-content\/uploads\/2022\/10\/image-11-768x389.png 768w, https:\/\/xiaoenjiyao.com\/wp-content\/uploads\/2022\/10\/image-11-880x445.png 880w, https:\/\/xiaoenjiyao.com\/wp-content\/uploads\/2022\/10\/image-11.png 1213w\" sizes=\"auto, (max-width: 751px) 100vw, 751px\" \/><figcaption class=\"wp-element-caption\"><em>J Clin Invest . 2019 Dec 2;129(12):5074-5076.<\/em><\/figcaption><\/figure>\n<\/div>\n\n\n<p class=\"wp-block-paragraph\">\u7ea2\u7ec6\u80de\u8868\u9762\u6709\u5341\u4f59\u79cd\u6291\u5236\u8865\u4f53\u901a\u8def\u6d3b\u5316\u7684\u86cb\u767d\uff0c\u5982GPI-\u951a\u5b9a\u86cb\u767d\u3002<\/p>\n\n\n\n<p 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