{"id":496,"date":"2022-10-20T00:16:17","date_gmt":"2022-10-19T16:16:17","guid":{"rendered":"https:\/\/xiaoenjiyao.com\/?p=496"},"modified":"2022-10-20T00:16:17","modified_gmt":"2022-10-19T16:16:17","slug":"%e5%a6%82%e4%bd%95%e8%ae%b0%e4%bd%8f%e6%89%80%e6%9c%89fda%e6%89%b9%e5%87%86%e7%94%9f%e7%89%a9%e8%8d%af%ef%bc%9f-%e8%a1%a5%e4%bd%93c5%e6%8a%91%e5%88%b6%e5%89%82-ravulizumab-%e9%9b%b7%e5%a4%ab","status":"publish","type":"post","link":"https:\/\/xiaoenjiyao.com\/?p=496","title":{"rendered":"\u5982\u4f55\u8bb0\u4f4f\u6240\u6709FDA\u6279\u51c6\u751f\u7269\u836f\uff1f| \u8865\u4f53C5\u6291\u5236\u5242 | Ravulizumab \u96f7\u592b\u5229\u73e0\u5355\u6297 | \u957f\u6548\u7248\u4f9d\u5e93\u73e0\u5355\u6297"},"content":{"rendered":"\n<p>\u7528\u56fe\u50cf\u8bb0\u5fc6\u7684\u65b9\u6cd5\uff0c\u4e00\u4e2a\u836f\u4e00\u5f20\u56fe\uff0c\u8bb0\u4f4f\u6240\u6709FDA\u6279\u51c6\u4e0a\u5e02\u751f\u7269\u5236\u5242\u7684\u540d\u79f0\uff0c\u9776\u70b9\uff0c\u9002\u5e94\u75c7\u7b49\u4fe1\u606f\u3002<\/p>\n\n\n\n<p>Ravulizumab\u540c\u6837\u662f\u7531\u745e\u58eb\u7f55\u89c1\u75c5\u5de8\u5934Alexion\uff08\u4e9a\u529b\u5144\uff09\u516c\u53f8\uff082021\u88abAZ\u6536\u8d2d\uff09\u7814\u53d1\u7684\u4e00\u6b3eC5\u8865\u4f53\u6291\u5236\u5242\u3002<\/p>\n\n\n\n<p>\u8be5\u836f2018\u5e74\u83b7\u7f8e\u56fdFDA\u6279\u51c6\u4e0a\u5e02\uff08ULTOMIRIS<sup>\u00ae<\/sup>Ravulizumab\uff09\u3002\u56fd\u5185\u6682\u672a\u4e0a\u5e02\uff0c\u4e5f\u672a\u67e5\u5230CDE\u6ce8\u518c\u7533\u62a5\u4fe1\u606f\uff0c\u6587\u732e\u4e2d\u79f0\u5176\u4e3a\u96f7\u592b\u5229\u73e0\u5355\u6297\u3002<\/p>\n\n\n\n<p>\u622a\u81f3\u76ee\u524dFDA\u6279\u51c6\u9002\u5e94\u75c7\u4e3a\uff1a\u9635\u53d1\u6027\u7761\u7720\u6027\u8840\u7ea2\u86cb\u767d\u5c3f\u75c7\uff08PNH\uff09\u3001\u975e\u5178\u578b\u6eb6\u8840\u6027\u5c3f\u6bd2\u75c7\u7efc\u5408\u5f81\uff08aHUS\uff09\u3001\u5168\u8eab\u578b\u91cd\u75c7\u808c\u65e0\u529b\uff08gMG\uff09\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">1\u3001\u4f5c\u7528\u673a\u5236<\/h2>\n\n\n\n<p>\u96f7\u592b\u5229\u73e0\u5355\u6297\u4f5c\u7528\u673a\u5236\u4e0e\u524d\u6587\u4f9d\u5e93\u73e0\u5355\u6297\u4e00\u81f4\uff0c\u5747\u4e3a\u8865\u4f53C5\u6291\u5236\u5242\uff0c\u9002\u5e94\u75c7\u4e5f\u4e00\u81f4\uff0c\u533a\u522b\u5728\u4e8e\u7ed9\u836f\u5468\u671f\u4e0d\u540c\u3002<\/p>\n\n\n\n<p>\u4ee5\u666e\u901a\u6210\u5e74PNH\u60a3\u8005\u4e3a\u4f8b\uff0c\u4f9d\u5e93\u73e0\u5355\u6297\u7ed9\u836f\u65b9\u5f0f\u4e3a\u524d4\u5468qw\uff0c\u4e4b\u540eq2w\u3002\u800c\u96f7\u592b\u5229\u73e0\u5355\u6297\u7ed9\u836f\u65b9\u5f0f\u4e3aq8w\u3002\u56e0\u6b64\u53ef\u4ee5\u628a\u96f7\u592b\u5229\u73e0\u5355\u6297\u770b\u6210\u662f\u957f\u6548\u7248\u4f9d\u5e93\u73e0\u5355\u6297\u3002<\/p>\n\n\n\n<p><strong>\u96f7\u592b\u5229\u73e0\u5355\u6297\u957f\u6548\u673a\u5236<\/strong><\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full is-resized\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/xiaoenjiyao.com\/wp-content\/uploads\/2022\/10\/image-21.png\" alt=\"\" class=\"wp-image-497\" width=\"628\" height=\"656\" srcset=\"https:\/\/xiaoenjiyao.com\/wp-content\/uploads\/2022\/10\/image-21.png 954w, https:\/\/xiaoenjiyao.com\/wp-content\/uploads\/2022\/10\/image-21-287x300.png 287w, https:\/\/xiaoenjiyao.com\/wp-content\/uploads\/2022\/10\/image-21-768x803.png 768w, https:\/\/xiaoenjiyao.com\/wp-content\/uploads\/2022\/10\/image-21-880x921.png 880w\" sizes=\"auto, (max-width: 628px) 100vw, 628px\" \/><figcaption><em>J Clin Pharm Ther . 2022 Jul;47(7):1081-1087.<\/em><\/figcaption><\/figure>\n<\/div>\n\n\n<p>\u4e24\u6b3e\u6297\u4f53\u836f\u7269\u7684\u8865\u4f53C5\u5728\u7ec6\u80de\u5185\u6e05\u9664\u8fc7\u7a0b\u4e0d\u540c\u3002<\/p>\n\n\n\n<p>\u4f9d\u5e93\u73e0\u5355\u6297\u7ed3\u5408\u8865\u4f53C5\u540e\uff0c\u5185\u541e\u8fdb\u5165\u7ec6\u80de\u5185\uff0c\u968f\u7740pH\u4e0b\u964d\uff0c\u6297\u4f53\u4e0eC5\u4e00\u8d77\u88ab\u6eb6\u9176\u4f53\u964d\u89e3\u3002\uff08\u56feA\uff09<\/p>\n\n\n\n<p>\u96f7\u592b\u5229\u73e0\u5355\u6297\u91c7\u7528\u518d\u5faa\u73af\u6297\u4f53\u6280\u672f\uff0c\u7ed3\u5408\u8865\u4f53C5\u5185\u541e\u8fdb\u5165\u7ec6\u80de\u540e\uff0c\u5728\u9178\u6027\u6761\u4ef6\u4e0b\u4e0e\u65b0\u751f\u513fFcRn\u53d7\u4f53\u7ed3\u5408\uff0cFcRn\u80fd\u4fdd\u62a4\u6297\u4f53\uff0c\u4e0d\u88ab\u6eb6\u9176\u4f53\u964d\u89e3\uff0c\u5b8c\u6574\u7684\u6297\u4f53\u518d\u6b21\u79bb\u5f00\u5185\u76ae\u7ec6\u80de\uff0c\u5faa\u73af\u4f7f\u7528\uff0c\u4ece\u800c\u5ef6\u957f\u4e86\u836f\u7269\u534a\u8870\u671f\u3002\uff08\u56feB\uff09<\/p>\n\n\n\n<p>\uff08\u4e0e\u524d\u6587\u4e2dIL-6\u62ee\u6297\u5242\uff0c\u8428\u7279\u5229\u73e0\u5355\u6297\u4f5c\u4e3a\u957f\u6548\u6258\u73e0\u5355\u6297\u7684\u673a\u5236\u4e00\u81f4\uff09<\/p>\n\n\n\n<p><a href=\"https:\/\/xiaoenjiyao.com\/?p=123\">\u767d\u4ecb\u7d20-6R\uff08IL-6R\uff09\u62ee\u6297\u5242 | \u5b89\u9002\u5e73<sup>\u00ae<\/sup>\u8428\u7279\u5229\u73e0\u5355\u6297<\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">2\u3001\u9002\u5e94\u75c7<\/h2>\n\n\n\n<p><strong>\u96f7\u592b\u5229\u73e0\u5355\u6297FDA\u9002\u5e94\u75c7<\/strong><\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full is-resized\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/xiaoenjiyao.com\/wp-content\/uploads\/2022\/10\/image-22.png\" alt=\"\" class=\"wp-image-498\" width=\"555\" height=\"203\" srcset=\"https:\/\/xiaoenjiyao.com\/wp-content\/uploads\/2022\/10\/image-22.png 978w, https:\/\/xiaoenjiyao.com\/wp-content\/uploads\/2022\/10\/image-22-300x110.png 300w, https:\/\/xiaoenjiyao.com\/wp-content\/uploads\/2022\/10\/image-22-768x281.png 768w, https:\/\/xiaoenjiyao.com\/wp-content\/uploads\/2022\/10\/image-22-880x322.png 880w\" sizes=\"auto, (max-width: 555px) 100vw, 555px\" \/><figcaption><em>\u8be5\u836f\u7269\u76ee\u524d\u56fd\u5185\u672a\u6279\u51c6\u4e0a\u5e02<\/em><\/figcaption><\/figure>\n<\/div>\n\n\n<p>Ravulizumab\u96f7\u592b\u5229\u73e0\u5355\u6297FDA\u6279\u51c6\u7684\u9002\u5e94\u75c7\u5305\u62ec\uff1a<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>\u9635\u53d1\u6027\u7761\u7720\u6027\u8840\u7ea2\u86cb\u767d\u5c3f\u75c7(PNH)<\/li><li>\u975e\u5178\u578b\u6eb6\u8840\u6027\u5c3f\u6bd2\u75c7\u7efc\u5408\u5f81\uff08aHUS\uff09<\/li><li>\u6297\u4e59\u9170\u80c6\u78b1\u53d7\u4f53\uff08AchR\uff09\u6297\u4f53\u9633\u6027\u7684\u5168\u8eab\u91cd\u75c7\u808c\u65e0\u529b\uff08gMG\uff09<\/li><\/ul>\n\n\n\n<p>\u5404\u4e2a\u9002\u5e94\u75c7\u7684\u4ecb\u7ecd\u53ef\u53c2\u89c1\u524d\u6587\u4f9d\u5e93\u73e0\u5355\u6297\u3002<\/p>\n\n\n\n<p><a href=\"https:\/\/xiaoenjiyao.com\/?p=480\">\u8865\u4f53C5\u6291\u5236\u5242 | \u8212\u7acb\u745e\u200b<sup>\u00ae<\/sup>\u4f9d\u5e93\u73e0\u5355\u6297<\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">3\u3001\u56fe\u50cf\u8bb0\u5fc6<\/h2>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full is-resized\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/xiaoenjiyao.com\/wp-content\/uploads\/2022\/10\/C5-ravu-no-gap.jpg\" data-gif=\"https:\/\/xiaoenjiyao.com\/wp-content\/uploads\/2022\/10\/C5-ravu-no.gif\" alt=\"\" class=\"wp-image-499\" width=\"571\" height=\"387\"\/><figcaption>\u96f7\u950b\u540c\u5fd7\u6325\u821e\u4e24\u628a\u957f\u9570\u5200\uff0c\u6253\u5f97\u5c01\u8d44\u4fee\u4eec\u4e00\u53ea\u773c\u775b\u8037\u62c9\uff0c\u4e24\u4e2a\u80be\u6d41\u8840\u3002<\/figcaption><\/figure>\n<\/div>\n\n\n<p>\u4e24\u628a\u9570\u5200\u5f62\u72b6\uff0c\u4e00\u628a\u4ee3\u8868C\uff0c\u4e00\u628a\u4ee3\u88685\u3002\u9570\u5200\u5f88\u957f\uff0c\u4ee3\u8868\u957f\u6548\u8865\u4f53C5\u6291\u5236\u5242\u3002<\/p>\n\n\n\n<p>\u96f7\u950b\u540c\u5fd7\u53d6\u8c10\u97f3\u4ee3\u8868\u96f7\u592b\u5229\u73e0\u5355\u6297\u3002<\/p>\n\n\n\n<p>\u4e00\u53ea\u773c\u775b\u8037\u62c9\u662f\u91cd\u75c7\u808c\u65e0\u529b\u7684\u5178\u578b\u8868\u73b0\u3002<\/p>\n\n\n\n<p>\u6d41\u8840\u7684\u80be\u4ee3\u8868\u9635\u53d1\u6027\u7761\u7720\u6027\u8840\u7ea2\u86cb\u767d\u5c3f\u75c7\u3001\u975e\u5178\u578b\u6eb6\u8840\u6027\u5c3f\u6bd2\u75c7\u7efc\u5408\u5f81\u3002<\/p>\n\n\n\n<p>\u4f60\u8bb0\u4f4f\u4e86\u4e48\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u7528\u56fe\u50cf\u8bb0\u5fc6\u7684\u65b9\u6cd5\uff0c\u4e00\u4e2a\u836f\u4e00\u5f20\u56fe\uff0c\u8bb0&#8230;<\/p>\n","protected":false},"author":1,"featured_media":500,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[3],"tags":[],"class_list":["post-496","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-3","wpcat-3-id"],"_links":{"self":[{"href":"https:\/\/xiaoenjiyao.com\/index.php?rest_route=\/wp\/v2\/posts\/496","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/xiaoenjiyao.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/xiaoenjiyao.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/xiaoenjiyao.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/xiaoenjiyao.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=496"}],"version-history":[{"count":1,"href":"https:\/\/xiaoenjiyao.com\/index.php?rest_route=\/wp\/v2\/posts\/496\/revisions"}],"predecessor-version":[{"id":501,"href":"https:\/\/xiaoenjiyao.com\/index.php?rest_route=\/wp\/v2\/posts\/496\/revisions\/501"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/xiaoenjiyao.com\/index.php?rest_route=\/wp\/v2\/media\/500"}],"wp:attachment":[{"href":"https:\/\/xiaoenjiyao.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=496"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/xiaoenjiyao.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=496"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/xiaoenjiyao.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=496"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}