{"id":624,"date":"2022-11-24T21:13:57","date_gmt":"2022-11-24T13:13:57","guid":{"rendered":"https:\/\/xiaoenjiyao.com\/?p=624"},"modified":"2022-11-24T21:13:57","modified_gmt":"2022-11-24T13:13:57","slug":"%e5%a6%82%e4%bd%95%e8%ae%b0%e4%bd%8f%e6%89%80%e6%9c%89fda%e6%89%b9%e5%87%86%e7%94%9f%e7%89%a9%e8%8d%af%ef%bc%9f-%e6%8a%97%e8%a1%80%e5%b0%8f%e6%9d%bf%e8%8d%af%e6%b1%87%e6%80%bb-abciximab-%e9%98%bf","status":"publish","type":"post","link":"https:\/\/xiaoenjiyao.com\/?p=624","title":{"rendered":"\u5982\u4f55\u8bb0\u4f4f\u6240\u6709FDA\u6279\u51c6\u751f\u7269\u836f\uff1f| \u6297\u8840\u5c0f\u677f\u836f\u6c47\u603b | Abciximab \u963f\u6614\u5355\u6297 | \u9632\u6b62\u8840\u6813\u5f62\u6210"},"content":{"rendered":"\n

\u7528\u56fe\u50cf\u8bb0\u5fc6\u7684\u65b9\u6cd5\uff0c\u4e00\u4e2a\u836f\u4e00\u5f20\u56fe\uff0c\u8bb0\u4f4f\u6240\u6709FDA\u6279\u51c6\u4e0a\u5e02\u751f\u7269\u5236\u5242\u7684\u540d\u79f0\uff0c\u9776\u70b9\uff0c\u9002\u5e94\u75c7\u7b49\u4fe1\u606f\u3002<\/p>\n\n\n\n

Abciximab \u963f\u6614\u5355\u6297\u662f\u7531\u5f3a\u751f\uff08Janssen\uff09\u516c\u53f8\u7814\u53d1\u7684\u4e00\u79cd\u6297\u4f53Fab\u7247\u6bb5\uff0c\u9009\u62e9\u6027\u963b\u65ad\u8840\u5c0f\u677f\u7cd6\u86cb\u767d\u2161b\/\u2162a\u53d7\u4f53\uff0c\u9632\u6b62\u8840\u5c0f\u677f\u805a\u96c6\u3002<\/p>\n\n\n\n

\u8be5\u836f1994\u5e74\u83b7\u7f8e\u56fdFDA\u6279\u51c6\u4e0a\u5e02\uff08ReoPro\u00ae<\/sup>\u00a0Abciximab\uff09\u3002\u56fd\u5185\u672a\u4e0a\u5e02\u3002<\/p>\n\n\n\n

1\u3001\u4f5c\u7528\u673a\u5236<\/h2>\n\n\n\n

\u524d\u6587\u8ba8\u8bbaCaplacizumab \u5361\u666e\u8d5b\u73e0\u5355\u6297\u65f6\uff0c\u5df2\u7ecf\u8bf4\u8fc7\uff0c\u4eba\u4f53\u4e2d\u8840\u7ba1\u6027\u8840\u53cb\u75c5\u56e0\u5b50\uff08VWF\uff09\u4f1a\u81ea\u53d1\u7ed3\u5408\u8840\u5c0f\u677f\uff0c\u4ea7\u751f\u8840\u5c0f\u677f\u805a\u96c6\u3002\u5361\u666e\u8d5b\u73e0\u5355\u6297\u901a\u8fc7\u963b\u65adVWF\u8868\u9762\u7684\u7ed3\u5408\u4f4d\u70b9\uff0c\u53ef\u4ee5\u964d\u4f4e\u8840\u5c0f\u677f\u805a\u96c6\u3002<\/p>\n\n\n\n

\u53cd\u8fc7\u6765\uff0c\u5982\u679c\u76f4\u63a5\u963b\u65ad\u8840\u5c0f\u677f\u8868\u9762\u7684\u7ed3\u5408\u4f4d\u70b9\uff0c\u5982\u963b\u65ad\u8840\u5c0f\u677f\u7cd6\u86cb\u767d\u2161b\/\u2162a\u53d7\u4f53\uff08GPIIb\/IIIa\uff09\uff0c\u540c\u6837\u53ef\u4ee5\u8d77\u5230\u964d\u4f4e\u8840\u5c0f\u677f\u805a\u96c6\u7684\u4f5c\u7528\u3002<\/p>\n\n\n\n

\u6297\u8840\u6813\u836f\u7269\u5206\u7c7b<\/strong><\/p>\n\n\n

\n
\"\"<\/figure>\n<\/div>\n\n\n

\u76ee\u524d\u6297\u8840\u6813\u836f\u7269\u4e3b\u8981\u5206\u6210\u9884\u9632\u8840\u6813\u5f62\u6210\u7684\u6297\u51dd\u3001\u6297\u8840\u5c0f\u677f\u836f\u7269\uff0c\u4ee5\u53ca\u4f7f\u5df2\u7ecf\u5f62\u6210\u7684\u8840\u6813\u6eb6\u89e3\u7684\u7ea4\u6eb6\u836f\u7269\u3002<\/p>\n\n\n\n

\u6297\u51dd\u836f\u7269\u4e3b\u8981\u4f5c\u7528\u4e8e\u51dd\u8840\u7ea7\u8054\u53cd\u5e94\u5404\u6b65\u9aa4\uff0c\u5173\u4e8e\u6297\u51dd\u8840\u836f\u7269\u7684\u5206\u7c7b\u548c\u4f5c\u7528\u673a\u5236\uff0c\u53ef\u4ee5\u53c2\u89c1\u524d\u9762\u7684\u5185\u5bb9\u3002<\/p>\n\n\n\n

\u6297\u8840\u5c0f\u677f\u836f\u7269\u7684\u673a\u5236\u9776\u70b9<\/strong><\/p>\n\n\n

\n
\"\"<\/figure>\n<\/div>\n\n\n

\u7cd6\u86cb\u767dGP \u2161b\/\u2162a\u662f\u8840\u5c0f\u677f\u8868\u9762\u7684\u53d7\u4f53\uff0c\u4e3b\u8981\u4ecb\u5bfc\u7ea4\u7ef4\u86cb\u767d\u539f\u3001\u8840\u7ba1\u6027\u8840\u53cb\u75c5\u56e0\u5b50\uff08VWF\uff09\u548c\u8840\u5c0f\u677f\u7684\u7ed3\u5408\uff0c\u4ece\u800c\u4f7f\u8840\u5c0f\u677f\u53d1\u751f\u4ea4\u8054\uff0c\u5f15\u8d77\u8840\u5c0f\u677f\u805a\u96c6\u3002<\/p>\n\n\n\n

\u8be5\u8fc7\u7a0b\u53d7\u4e24\u6761\u901a\u8def\u8c03\u63a7\uff1a<\/p>\n\n\n\n

1\u3001\u73af\u6c27\u5316\u9176COX-1\u8def\u5f84\u3002\u6fc0\u6d3bGP\u00a0\u2161b\/\u2162a\uff0c\u4fc3\u4f7f\u8840\u5c0f\u677f\u805a\u96c6\u3002
2\u3001\u4f4d\u4e8e\u8840\u5c0f\u677f\u8868\u9762\u7684P2Y12\u53d7\u4f53\u7ed3\u5408\u4e8c\u78f7\u9178\u817a\u82f7\uff08ADP\uff09\u3002\u6fc0\u6d3bGP \u2161b\/\u2162a\uff0c\u4fc3\u4f7f\u8840\u5c0f\u677f\u805a\u96c6\u3002<\/p>\n\n\n\n

\u6297\u8840\u5c0f\u677f\u836f\u7269<\/strong><\/p>\n\n\n

\n
\"\"<\/figure>\n<\/div>\n\n\n

\u6c2f\u5421\u683c\u96f7\u3001\u66ff\u683c\u745e\u6d1b\u7b49\u836f\u7269\uff0c\u963b\u65adADP\u4e0eP2Y12\u7ed3\u5408\u3002\u6291\u5236\u8840\u5c0f\u677f\u805a\u96c6\u3002<\/p>\n\n\n\n

\u5c0f\u5242\u91cf\u963f\u53f8\u5339\u6797\u53d1\u6325\u6291\u5236COX-1\u4f5c\u7528\uff08\u5e38\u89c4\u5242\u91cf\u963f\u53f8\u5339\u6797\u8fd8\u6291\u5236COX-2\u53d1\u6325\u89e3\u70ed\u9547\u75db\u4f5c\u7528\uff09\uff0c\u6291\u5236\u8840\u5c0f\u677f\u805a\u96c6\u3002<\/p>\n\n\n\n

\u963f\u6614\u5355\u6297\u76f4\u63a5\u963b\u65adGP \u2161b\/\u2162a\uff0c\u6291\u5236\u8840\u5c0f\u677f\u805a\u96c6\u3002<\/p>\n\n\n\n

\u963f\u6614\u5355\u6297\u7684\u7ed3\u6784<\/strong><\/p>\n\n\n

\n
\"\"
Am Heart J . 1999 Jul;138(1 Pt 2):S33-8.<\/em><\/figcaption><\/figure>\n<\/div>\n\n\n

\u963f\u6614\u5355\u6297\u7684\u7ed3\u6784\u4e3a\uff1a<\/p>\n\n\n\n

\u53bb\u9664\u9f20\u6e90\u5355\u6297\u7684Fc\u6bb5\uff0c\u83b7\u5f97\u5355\u4e2aFab\u6bb5\uff0c\u518d\u5bf9Fab\u7684\u6052\u5b9a\u533a\u8fdb\u884c\u4eba\u6e90\u5316\u6539\u9020\uff0c\u83b7\u5f97\u7684\u4eba\u9f20\u5d4c\u5408\u6297\u4f53Fab\u6bb5\u3002<\/p>\n\n\n\n

2\u3001\u9002\u5e94\u75c7<\/h2>\n\n\n\n

\u963f\u6614\u5355\u6297\u4f5c\u4e3a\u7ecf\u76ae\u51a0\u72b6\u52a8\u8109\u4ecb\u5165\u6cbb\u7597\uff08PCI\uff09\u7684\u8f85\u52a9\u836f\u7269\uff0c\u7528\u4e8e\u9884\u9632\u5fc3\u810f\u8840\u7ba1\u5835\u585e\u5f15\u8d77\u5fc3\u808c\u6025\u6027\u7f3a\u8840\u3002<\/p>\n\n\n\n

3\u3001\u56fe\u50cf\u8bb0\u5fc6<\/h2>\n\n\n
\n
\"\"
\u5b89\u897f\u6559\u7ec3\u5927\u529b\u704c\u7bee\uff0c\u7bee\u677f\u88ab\u4ed6\u6253\u7834\u5e76\u6d41\u51fa\u4e86\u8840\u3002<\/figcaption><\/figure>\n<\/div>\n\n\n

\u5b89\u897f\u6559\u7ec3\u4ee3\u8868\u836f\u7269\uff0c\u963f\u6614\u5355\u6297\u3002<\/p>\n\n\n\n

\u7bee\u677f\u6d41\u8840\uff0c\u4ee3\u8868\u836f\u7269\u673a\u5236\u53ca\u9002\u5e94\u75c7\uff0c\u6297\u8840\u5c0f\u677f\u805a\u96c6\u3002<\/p>\n\n\n\n

\u4f60\u8bb0\u4f4f\u4e86\u4e48\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"

\u7528\u56fe\u50cf\u8bb0\u5fc6\u7684\u65b9\u6cd5\uff0c\u4e00\u4e2a\u836f\u4e00\u5f20\u56fe\uff0c\u8bb0…<\/p>\n","protected":false},"author":1,"featured_media":631,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[3],"tags":[],"class_list":["post-624","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-3","wpcat-3-id"],"_links":{"self":[{"href":"https:\/\/xiaoenjiyao.com\/index.php?rest_route=\/wp\/v2\/posts\/624","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/xiaoenjiyao.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/xiaoenjiyao.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/xiaoenjiyao.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/xiaoenjiyao.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=624"}],"version-history":[{"count":2,"href":"https:\/\/xiaoenjiyao.com\/index.php?rest_route=\/wp\/v2\/posts\/624\/revisions"}],"predecessor-version":[{"id":634,"href":"https:\/\/xiaoenjiyao.com\/index.php?rest_route=\/wp\/v2\/posts\/624\/revisions\/634"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/xiaoenjiyao.com\/index.php?rest_route=\/wp\/v2\/media\/631"}],"wp:attachment":[{"href":"https:\/\/xiaoenjiyao.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=624"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/xiaoenjiyao.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=624"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/xiaoenjiyao.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=624"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}